SLITRK1 and Timothy syndrome: On the other hand, genetic association studies and haplotype analyses could not rule out the implication of SLITRK1 in TS etiology either via the existence of risk factors in LD with SLITRK1 (Miranda et al., 2009) or as of yet unidentified SLITRK1 regulatory variants (Karagiannidis et al., 2012).