More specifically, we injected heterozygous SERT knock-out and wildtype rats prenatally with a moderate dose (400 mg/kg s.c.)of valproate and investigated the behavior of the offspring in two models for anxiety (elevated plus maze and novelty suppressed feeding) and two models assessing cognition and information processing (latent inhibition and prepulse inhibition). This evidence concerns the gene SLC6A4 and Anxiety.