In addition, we also found enhanced EMT (increased N-Cadherin and reduced E-Cadherin) and CSC phenotypes (CD44 and Oct-4) in the PC-3RR xenograft tumors compared to the PC-3 control tumor (Figure 1C), which is consistent with our previous in vitro studies with CaP-RR cell lines [8]. This evidence concerns the gene CDH2 and neoplasm.