A supervised comparison of LP-DLBCL against all other DLBCL cases revealed an overexpression of T cell- and macrophage-associated genes (GZMK, MT1H, C1QA, CD2, STAT1, CD3D, CD3G, SOD2, Table 1) in the LP-DLBCL. This evidence concerns the gene CD2 and diffuse large B-cell lymphoma.