We also interrogated the co-expression of the reported genes on the same data set (17157 genes from 244 colorectal adenocarcinoma cases); strikingly, IL1B, IL8 and CXCL1 display the highest correlation with IL1A, with a Pearson correlation of 0.66, 0.55 and 0.51 respectively. This evidence concerns the gene IL1A and colorectal adenocarcinoma.