TCGA breast studies demonstrated a significant 14.7-fold and 9.3-fold decrease in DACT2 mRNA expression in Invasive Ductal Breast Carcinoma (IDBC) and Invasive Lobular Breast Carcinoma (ILBC), respectively, and an 11.2-fold decrease in Invasive Breast Carcinoma (IBC) compared to normal breast tissues (Figure 2C). This evidence concerns the gene DACT2 and breast ductal adenocarcinoma.