In addition to its prothrombotic activities, TF elevation isassociated to TLR3-dependent interferon beta (IFN-β) expression (Bode & Mackman 2015, Liang et al.2015) that suppresses IFN-γ-induced antimicrobial responses in human leprosy(Teles et al. 2013, 2015). This evidence concerns the gene TLR3 and leprosy.