IL6 and Insulin resistance: Otherwise, a number of clinical epidemiological studies have reported that inflammatory markers, such as high-sensitivity CRP(C-reactive protein), tumor necrosis factor(TNF-α), and interleukin-6(IL-6), are associated with insulin resistance and visceral fat accumulation [10], and an inverse correlation has been detected between ADPN levels and the visceral fat area (VFA) [11].