RPS4Y1 and familial pancreatic carcinoma: RPS4Y1, a Y chromosome-linked gene [45], was found to functionally interact with a translation factor EEF1A2. While these proteins were linked to metabolic processes EEF1A2 may indirectly associate with cell adhesion related pathways as it has been shown to regulate MMP-9 expression and thereby influence migration and metastatic properties of pancreatic cancer cells [46].