Therefore, future research efforts should also focus attention on identification of CRC-specific O-glycans on differentially expressed mucins (MUC1, MUC2, MUC4, MUC5AC, and MUC17) and develop CRC-specific glycopeptide microarrays for serum profiling of patients harboring colorectal polyps with malignant potential. The gene discussed is MUC4; the disease is colorectal carcinoma.