Due to the paucity of information regarding the association of MUC17 with BRAF mutation, CpG island methylator phenotype (CIMP), microsatellite instability (MSI) and microsatellite instability-high (MSI-H) colon carcinomas, additional studies addressing these aspects would help establish MUC17 as a marker of neo-transformation through the serrated neoplasia pathway. This evidence concerns the gene BRAF and colon carcinoma.