CD4 and myeloid sarcoma: In fact, UCMSC-primed Tregs from MS reduced the proliferation index of PHA-stimulated allogeneic CD4+CD25- Teffs from heathy donors to the same degree as that produced by Tregs from heathy donors (Figure 2A); i.e., no significant difference was detected in the suppressive capacity of naïve Tregs from healthy donors and UCMSC-primed Tregs from MS patients, suggesting that UCMSC-co-cultures may have reversed the impaired suppressive function of Tregs from MS.