In addition, infection is strongly associated with increased transcription from a number of cytokine and chemokine genes, including IL1A and CXCL8 (IL-8), that contribute to recruitment of new neutrophil hosts, and to inflammatory tissue injury and disease (Klein et al., 2000; Akkoyunlu et al., 2001; Scorpio et al., 2004). The gene discussed is CXCL8; the disease is infection.