W Chien et al in their study Molecular biology of thyroid cancer, indicate the presence of chromosomal translocation t(2;3)(q13;p25), PAX8/PPARγ rearrangement, with a fusion of PAX8, thyroid-specific transcription factor to PPARγ, nuclear hormone receptor involved in differentiation of cells. The gene discussed is PAX8; the disease is thyroid gland carcinoma.