AKT1 and thyroid gland carcinoma: Several molecular alterations were identified in last year’s, which included genetic and epigenetic alterations in signalling pathways, like MAPK (Mitogen-activated protein kinases are known also as ERK – extracellular signal-regulated kinases) pathway responsible for tumour initiation and PI3K-AKT signalling pathway for progression and dedifferentiation of thyroid carcinomas.