LCK and metastatic neoplasm: In contrast, the peptides derived from Lck or MRP3 were chosen when the IgGs reactive to them were detectable in prevaccination plasma, since Lck or MRP3 was highly expressed in the metastatic tumors or tumor cells after chemotherapy, respectively [5–9], and thus negative expression of these two antigens on 10 primary esophageal tumor samples before chemotherapy was expected as reported previously.