In PPV without PKM arm, they were dermatologic reactions at the injection sites (64%), ALP elevation (55%) (P < 0.01 versus PPV with PKM arm), AST elevation (45%) (P < 0.01), hypoalbuminemia (45%), anemia (36%), ALT elevation (36%) (P < 0.01), and GGT elevation (36%) (P < 0.01). The gene discussed is GPT; the disease is Hypoalbuminemia.