Visceral adiposity has been complicated with negative effects including insulin resistance and the elevated production of pro-inflammatory molecules leptin (LEP), resistin, tumor necrosis factor-α (TNF-α), IL-6, hypoxia-inducible factor 1 (HIF-1) and adipocyte fatty-acid binding protein (A-FABP) (Weisberg et al., 2003; Wisse, 2004; Gregor and Hotamisligil, 2011; Spoto et al., 2014; Petrangeli et al., 2016). This evidence concerns the gene LEP and Insulin resistance.