Growth of neoplasm relied on angiogenesis34, and some platelet-derived cytokines related to tumor angiogenesis regulatory such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), platelet derived growth factor (PDGF) that have been found elevated in platelets of cancer patients in recent report35. This evidence concerns the gene FGF2 and neoplasm.