TALDO1 and infection: It should be mentioned that the reintroduction of TALDO1 into TALDO1 KO cells only partially rescued the levels of some metabolites (e.g. malate, fumarate, and 2-oxoglutarate), which could be due to the relatively short time-course of the experiment (24 h after infection) or, alternatively, the excess amount of exogenous TALDO1 isoforms as compared with the endogenous one (data not shown).