The pentosidine also associated with the aetiology of CKD and was highest in patients with hypertension/renal vascular disease, 40.6 (18.3–84.3) nmol/g albumin which was higher than in GN patients, 26.9 (9.2–64.4) nmol/g albumin (p<0.01), non-significantly different compared to DM, 33.0 (14.2–71.2) nmol/g albumin (p = 0.07) and higher compared to other aetiologies, 31.8 (11.3–76.0) nmol/g albumin (p<0.01). This evidence concerns the gene ALB and ganglioneuroma.