PTCH1 is one of the causative genes for nevoid basal cell carcinoma syndrome (a.k.a. basal cell nevus syndrome, OMIM# 109400), which includes OFC and TA as secondary features of its core characteristics, including also jaw cysts, basal cell tumors and skeletal abnormalities (Cobourne et al. 2009; Lam et al. 2013). Here, PTCH1 is linked to Abnormal jaw morphology.