While it is generally believed that a Th1-dominated immune response is critical to achieve a protective immune response against Salmonella infection in mice55, 56, 57, 58, 59, mucosal immunity represented by production of secretary IgA on the mucosal surface is also considered to play an important role in preventing Salmonella colonization in the thick mucus layer of the intestinal epithelium60, 61, 62. The gene discussed is CD79A; the disease is Salmonella Infections.