Previous studies have demonstrated the osteoinductive effects of BMP2 within skeletal muscle (Katagiri et al., 1994; Kaihara et al., 2004), and links are present between BMP‐induced ectopic bone formation and a rare genetic form of HO termed fibrodysplasia ossificans progressiva (FOP) (Shore et al., 2006). The gene discussed is BMP2; the disease is fibrodysplasia ossificans progressiva.