Ischemic stroke increased functional expression of all three channels studied here and we observed activated microglia predominantly expressing Kir2.1, which would correspond to the IL‐4 stimulated M(IL‐4) microglia described here, but also cells predominantly showing large KV1.3 currents similar to the M(LPS) cells in this study as well as cells exhibiting various combinations of KV1.3, KCa3.1 and Kir2.1 currents (Chen et al., 2015). Here, IL4 is linked to ischemic stroke.