We and others have previously used immunohistochemistry to demonstrate KV1.3 and KCa3.1 expression on activated microglia in human ischemic infarcts (Chen et al., 2015) and KV1.3 expression on microglia surrounding amyloid‐plaques in Alzheimer's disease (Rangaraju et al., 2015). This evidence concerns the gene KCNN4 and early-onset autosomal dominant Alzheimer disease.