Among the ten HCV encoded structural (core, E1, E2) and non-structural (P7, NS2, NS3, NS4A, NS4B, NS5A, NS5B) proteins [4], core, NS3, NS4B, and NS5A have been shown to directly activate oncogenic molecular pathways and promote tumor formation in vivo [5–8]. The gene discussed is KRAS; the disease is neoplasm.