This group includes homocystinurias, cerebrotendinous xanthomatosis, nonketotic hyperglycinemia, monoamine oxidase A deficiency, succinic semialdehyde dehydrogenase deficiency, creatine transporter defect, and alpha-/beta-mannosidosis. Here, ALDH5A1 is linked to hyperinsulinemic hypoglycemia, familial, 4.