Additionally, DDX5/p68 has been shown to allow for increased MBNL1 binding to the mutant CUG-expanded mRNA repeats which, in turn, can influence splicing events misregulated in DM1 as described for the cardiac Troponin T (TNNT2) pre-mRNA.48 Here, MBNL1 is linked to myotonic dystrophy type 1.