CFL1 and infection: Biochemical studies show that ADF/cofilin is capable of severing and depolymerizing actin filaments from their pointed ends (Carlier et al., 1997; Andrianantoandro and Pollard, 2006)., and the relaxation of the cytoskeleton in nematode feeding sites may open the way for a successful infection (de Almeida Engler et al., 2004).