The same antibody used to purify ANF-RGC to homogeneity from adrenocortical carcinoma and from adrenal cortex indicated a much wider expression including testes (Marala and Sharma, 1988), neurons located in the ventral horn region of rat spinal cord, cerebellar Purkinje cells, and renal glomerular cells (Ballermann et al., 1988). The gene discussed is NPPA; the disease is adrenal cortex carcinoma.