IFNG and parasitic infectious disease: This 3D7 vaccine strain-specificity was also shown using PBMCs from HuAd5-immunized subjects; one HLA B*58 subject (v194), who was not sterilely protected but showed a significant delay to parasitemia [2], was also positive with the HLA B*58 epitope but not the 7G8 HLA B*58 epitope; and two non-protected subjects (v135 and v179, each expressing HLA A*32:01 that is A*01 supertype) who were weakly positive with the 3D7 B*58 (recognized through a different HLA, A*01), whereas the 7G8 B*58 epitope did not recall ELISpot IFN-γ responses from either of these subjects (Table 2; Fig 2, Panel D).