As in Study 1, we first analyzed for group differences (BDNF Val/Val vs. BDNF Val/Met or Met/Met; TPH2 G/G vs. TPH2 T/G or T/T; and their interaction) in inhibitory processing of negative emotion using an omnibus ANCOVA test, controlling for reported depression as well as emotion responses to the previous films. This evidence concerns the gene BDNF and major depressive disorder.