Given the biological heterogeneity of BCP-ALL, we analyzed the association between rs35837782 and rs4762284 genotypes, and the major subtypes of BCP-ALL, hyperdiploidy (that is, >50 chromosomes), ETV6-RUNX1 and others (Supplementary Table S6; Supplementary Figure S3). This evidence concerns the gene RUNX1 and acute lymphoblastic leukemia.