NFKB1 and neoplasm: In lipopolysaccharide-activated macrophages and epidermal cells treated with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA), black tea theaflavins and EGCG inhibited the phosphorylation of IκB, preventing NF-κB from translocating to the nucleus and binding to DNA36, 37.