Havrix and Twinrix shared 11 AE symptoms (i.e., ocular icterus, anaphylactic shock, aspartate aminotransferase level increased, chromaturia, abortion, pelvic pain, hepatitis A, vaginal haemorrhage, impaired work ability, alanine aminotransferase level increased, hepatic enzyme increased). This evidence concerns the gene GPT and anaphylaxis.