As shown in Figure 2A-2C, increased eIF5B expression was observed in tumors with a higher AFP level, larger tumors and vascular invasion (VI) (Figure 2A–2C) compared with tumors with a lower AFP level, smaller tumors and without VI, which has been reported to be an independent early recurrence factor after primary resection in patients with HCC [19]. This evidence concerns the gene AFP and hepatocellular carcinoma.