These results are consistent with those of other groups, who could show that metastasization metastasesin Rag-2 KO mouse models are stronger than in nude mice for several human cancer xenografts like sarcoma (Nanni et al., 2010), breast cancer (Nanni et al., 2012) or adenocarcinoma (Ye et al., 2015). This evidence concerns the gene RAG2 and breast carcinoma.