IDH2 and acute myeloid leukemia: IDH driver mutations are also found in acute myeloid leukemia (AML) (Mardis et al., 2009), cholangiocarcinoma (Borger et al., 2012), enchondroma (Amary et al., 2011, Pansuriya et al., 2011), chondrosarcoma (Amary et al., 2011), and occasionally, other tumors.