A genome-wide association study of bladder cancer that analyzed 12,254 individuals with bladder cancer and 53,395 controls uncovered three genomic regions associated with bladder cancer including a genetic variant of the UGT1A gene locus, rs11892031 (P = 1.0×10^-7; OR per C allele = .84, 95% CI = 0.79-0.89) [18]. Here, UGT1A1 is linked to urinary bladder carcinoma.