Because we did not succeed in establishing CD8+ lymphoma cell lines, we utilized previously generated MYC-induced Dnmt3a+/+ and Dnmt3a-/- T cell lymphoma cell lines [7], along with MSCV-IRES-p53-GFP overexpressing both p53 and EGFP [21], to evaluate the role of p53 in lymphomagenesis. This evidence concerns the gene CD8A and T-cell non-Hodgkin lymphoma.