We found marked activation of aurora kinase A (AURKA) and B (AURKB) in cells infected with WT but not ∆Vif viruses (Figure 6—figure supplement 1C), and confirmed this observation by comparing phosphorylation of sites listed on the PhosphoSitePlus (http://www.phosphosite.org/) kinase substrate database (Hornbeck et al., 2015) between WT and ∆Vif virus infections (Figure 6C). Here, AURKB is linked to viral infectious disease.