The marker of enterocyte death, intestinal fatty acid binding protein (I-FABP) [59] joins biomarkers of structural barrier disruption, including L/M and %L as well as A1AT and Reg1 as an indicator of monocyte responses to LPS bioactivity, sCD14 has also been associated with increased IL6, CRP, SAA, D-dimer and increased mortality in HIV-infected individuals [60], as well as directly measured LPS and I-FABP, all presumably reflecting an enteropathy with increased microbial (or microbial product) translocation [61]. The gene discussed is SAA1; the disease is Abnormal intestine morphology.