Interestingly, the number of CD4 T cells, B cells, dendritic cells (DCs) and myeloid-derived suppressor cells (MDSc) were significantly lower in the neutrophil-depleted mice treated at week 4 post-infection and analyzed at 12 weeks post-infection compared to untreated or isotype-treated mice (Fig 2A–2D). Here, CD4 is linked to infection.