A significantly higher percentage of CD3+ T (p < 0.04), CD8+ (p < 0.03), CD8+ CD45RO+ (p < 0.01), CD4+DR+ (p < 0.02, CD8+DR+ (p < 0.05), and CD8+ CD39+ (p < 0.02) cells were found in TT from an adenocarcinoma than in TT from a squamous cell carcinoma. This evidence concerns the gene CD4 and adenocarcinoma.