Notably, a previous study conducted on full-face PCa tissue samples from a small patient cohort (N = 46) using an antibody which does not discriminate between the individual TPα/TPβ isoforms found that expression of the TP was increased in the malignant relative to benign tissue, with advanced pathological stages and poorly-differentiated tumours having the highest expression levels [12]. Here, PLAT is linked to posterior cortical atrophy.