IPO11 and myalgic encephalomeyelitis/chronic fatigue syndrome: Importantly, high importin-11 expression was significantly associated with reduced 3-year OS, CSS, and CFS rates, and it was also an independent risk factor for CSS and CFS in the BCa patients, indicating that high expression of this gene stimulates BCa progression and that the CNV in IPO11 is a crucial component of the molecular mechanism of its overexpression.