IPO11 and myalgic encephalomeyelitis/chronic fatigue syndrome: The results demonstrated that importin-11 overexpression remained significantly associated with reductions in CSS (P = 0.018, hazard ratio of 3.191, 95% CI: 1.222 to 8.335) and CFS (P = 0.015, hazard ratio of 2.972, 95% CI: 1.235 to 7.150) (Table 2).