IFNA1 and bacterial infectious disease: The hsa-miR-548 family is involved in multiple biological processes, such as signaling pathways, immunity, and osteogenic differentiation, and some cancers [43–47]. hsa-miR-548 takes part in IFN signaling which responds to the virus and bacterial infections on the cell [46]. hsa-miR-548 also can turn down the host antiviral response by degradation of IFN-λ1 [43].