Of the 26 HLA-A alleles studied in Asian patients with vitiligo, four (HLA-A∗03, A∗10, A∗25, and A∗33) were significantly associated with increased risk of vitiligo and three (HLA-A∗09, A∗66, and Aw∗19) were associated with decreased risk. The gene discussed is HLA-A; the disease is vitiligo.