We evaluated the FCWAs influence on the in vitro cellular cytokine response to an inflammatory challenge with LPS in sarcoidosis and on the mRNA expression of the main pattern-recognition receptors (PRRs) for recognizing FCWAs and LPS, dectin-1, toll-like receptor 2 (TLR2), TLR4 and mannose receptor (MR). The gene discussed is CLEC7A; the disease is sarcoidosis.