The level of chemokines, such as monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1a (MIP-1a), has been found to increase in experimental stroke and low expression of chemokines is associated with reduced injury by inhibition or deficiency [78, 79], attributed to impairing leukocyte infiltration [80]. The gene discussed is CCL2; the disease is stroke disorder.