Increased susceptibility for OPMD risk with SNPs in GSTM1 (null), CCND1 (G870A), XPD (codon 751) and MMP3 (-1171; promotor region) was common to majority of populations (Asians, Caucasians, Brazilians and others). This evidence concerns the gene CCND1 and oculopharyngeal muscular dystrophy.