Suggestive markers of increased susceptibility for OPMD risk based on significant associations as reported by at least 2 or more studies worldwide included GSTM1 null genotype, CCND1 (G870A) with risk allele A, MMP3 (-1171; promotor region) with risk allele 5A, TNFα (308; rs800629) with risk allele A and XPD (codon 751) with risk allele C as well as p53 (codon72) with risk allele C in Indian populations. The gene discussed is TNF; the disease is oculopharyngeal muscular dystrophy.