IL27 and asthma: To test this hypothesis, we administered IL-27 to OVA-immunized mice at two concentrations (25 and 50 ng/mouse) twice a day for 7 days before the OVA challenge (after the second OVA sensitization) (Additional file 1: Figure S1A), and there seemed to be no obvious improvement in the mouse asthma model (Additional file 1: Figure S1B, C).