Results showed that NE feature and TNM stage were significantly correlated to DFS (p < 0.001 for NE feature and p = 0.004 TNM staging) and OS (p = 0.006 for NE feature and p < 0.001 for TNM staging), and expression of mutant p53 was correlated to DFS (p = 0.025) but not OS (p = 0.16) for NSCLC patients in Kaplan-Meier curve; however, COX regression analysis indicated that only NE feature had most significance as an independent risk factor for poor prognosis (Table 3). This evidence concerns the gene TP53 and non-small cell lung carcinoma.